Assessment of Fibrosis in Liver Biopsy. Progression and Regression
نویسنده
چکیده
Fibrosis is part of the liver alterations in most chronic liver diseases (CLD). The pattern of fibrosis appears to be related to the pathogenetic mechanism of disease, explaining the relative diagnostic usefulness of various patterns of fibrosis for the liver histopathologist. Semiquantitative evaluation of fibrosis is also an important issue supporting the central role of the biopsy since this feature is a major predictor for the prognosis of most CLD. Also, clinical and experimental evidences support the possible occurrence of fibrosis regression in appropriate conditions. Therefore liver biopsy remains an essential tool in the management of patients with chronic liver diseases.
منابع مشابه
Assessment of diagnostic value of DWI technique in the evaluation of liver fibrosis
Introduction: The liver fibrosis is caused by extracellular accumulation of cluster, glycos amino glycans and proteoglycans, which this extracellular accumulation may limit the penetration and molecular movement of water in the tissue, so the Diffusion weighted imaging(DWI) technique is due to the sensitivity to the movement and release of water molecules Can show this restrict...
متن کاملAssessment of transient elastography (FibroScan) for diagnosis of fibrosis in non-alcoholic fatty liver disease: A systematic review and meta-analysis
Background: Transient elastography (TE) is a new modality for the diagnosis of liver fibrosis caused by various etiologies. This study was conducted to determine the accuracy of TE in detecting the different stages of liver fibrosis in non-alcoholic fatty liver disease (NAFLD) patients. Methods: MEDLINE/PubMed, Embase, Ovid, Cochrane Library, American College of Physicians (ACP) Journal Club...
متن کاملBackground: Hepatic steatosis is commonly observed in patients with chronic hepatitis C (CHC). Many studies indicate a relationship between steatosis and fibrosis progression. The aim of this study was to analyze the prevalence of hepatic steatosis and related factors in Iranian CHC patients. Methods: One hundred and fifteen consecutive patients with CHC were enrolled which were treat...
متن کاملPrevalence of hepatic steatosis and associated factors in Iranian patients with chronic hepatitis C
Background: Hepatic steatosis is commonly observed in patients with chronic hepatitis C (CHC). Many studies indicate a relationship between steatosis and fibrosis progression. The aim of this study was to analyze the prevalence of hepatic steatosis and related factors in Iranian CHC patients. Methods: One hundred and fifteen consecutive patients with CHC were enrolled which were treat...
متن کاملDetermining the progression stages of liver fibrosis in patients with chronic hepatitis B
Introduction: Chronic hepatitis B (CHB) leads to liver fibrosis, its failure, and death in the long term. The stage of fibrosis in CHB patients can also be detected based on the biochemical markers. The aim of this study was to predict the state of liver fibrosis in CHB patients and determine the possibility of patients shifting from a given state to another one. Materials and Methods: This stu...
متن کامل